Popular pattern I have never fished: Perdigon.
Standard fly in the box that never gets used: Muddler Minnow.
In my mind flies based on other flies go together, like an Elk Hair Caddis vs a CDC variant, because I would readily use one or the other based on which was in the box. I like all those classics dryflyguy listed. It's fun to catch trout on a Royal Wulff, it's easy to see, and it can pull duty as a stylish bobber. And while my Muddler has not muddled for decades, I would use it if there weren't so many other streamers from which to choose. In spite of rumors to the contrary, streamers and wet flies do actually catch trout. The San Juans are just taking up space so no reason to replace with Squirmies.
