Yes, to your questions. Very good fishing in Williamsport area. Big three with 10 to 30 minutes from Williamsport are, Lycoming Creek, Loyalsock Creek, Big Pine Creek. Larger streams providing excellent fly fishing.
Now, on the larger streams fly patterns will vary from, midges, small and medium nymphs, wets and streamers. To put an exact fly, well it is better to be there. There are also many more.
What came to mind, to me, right away are 2 that are absolute breathtaking. First of 2, better known stream--------Rock Run. Second, an almost forgotten, Roaring Branch.
Rock Run, located in Ralston Pa. and Roaring Branch located a few miles north of Ralston.
Rock Run, is what memories are made of. Deep clear pools, waterfalls, ice cold water. Fish it and you will always remember it. I do think it may be possible to set up a tent. Check to see if this still applies. Take a friend. 2 cars is better than the walk back. Can be fished in three days from Yellow Dog Trail to mouth which dumps in the Lycoming. Different from any other stream.
Roaring Branch has some similar looks as to Rock Run but different in many ways. Roaring branch, no camping, fishing is allowed, walk in only. Posted and stocked by local clubs only. Since not much pressure, it is possible for some real beauties.
No real fuss on flies, dry flies 10, 12, 14 are perfect. Adams, Coachman, yellow body, green body, all colors are good. Trout need to feed up and are not picky. I generally start where a bridge crosses the stream and a horse farm is. I guess 5 miles up the branch road. Again, can be fished in 3 days. nice to have 2 cars.
As always, pack a nice lunch, keep area clean, take a camera and have fun! You will want pictures. Remember be polite to landowners and obey Pa. fishing laws.
Hope this helped. Since you are a young man, i will bet you want to fish "The Whole Stream". I know, i did. Over and over, Since i am a lot older now, larger streams are easier.
I will be truthful. I would rater fish these 2, catch nothing, than fish Spring in Bellefonte. anybody and everyone fishes Spring. You get a good feeling of accomplishment fishing the Ralston Pa. 2 goodies.
Maxima12