I get a chance to peek into noobies fly boxes quite often, and most times I see various patterns, but mostly all in one size (usually rather large).
In general, would rather fish out of a box with flies in various sizes, colors and shapes. Small to large - dark/dull/natural to light/bright/shiny - upright wing dries(for mayflies) and down wing ones (for caddis and stoneflies).
With specific hatches, think size first, form next (upright/down-wing), and color last (light or dark rather than exact color).
Try an Adams dry for all darker mayflies in size 10-20
Use a sulpher or cahill pattern in 12-18 for all light colored Mayflies
Get a tan Caddis pattern for light colors and a dark gray or green for darker ones, both in size 12 -18 to imitate caddis and stones.
Do the same for nymphs - small to big, light to dark, and add in some bright and shiny ones.
If your buy or tie flies as recommended above, you should find a suitable imitation to fool some fish.